Measurement of myocardial structure: 3d structure tensor analysis of high resolution MRI quantitatively compared to DT-MRI

  • Authors:

  • Stephen Gilbert;Mark Trew;Bruce Smaill;Aleksandra Radjenovic;Olivier Bernus

  • Affiliations:

  • Multidisciplinary Cardiovascular Research Centre, University of Leeds, UK,L'Institut de ryhtmologie et modélisation cardiaque, Unité Inserm 1045, Centre de Recherche Cardio-Thoracique, U ...;Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand;Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand;NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, UK;Multidisciplinary Cardiovascular Research Centre, University of Leeds, UK,L'Institut de ryhtmologie et modélisation cardiaque, Unité Inserm 1045, Centre de Recherche Cardio-Thoracique, U ...

  • Venue:
  • STACOM'12 Proceedings of the third international conference on Statistical Atlases and Computational Models of the Heart: imaging and modelling challenges
  • Year:
  • 2012

Quantified Score

Hi-index 0.00

Visualization

Abstract

The ventricular myocardium has a structure of branching laminae through which course regularly orientated fibers, an architecture important in excitation and contraction. DT-MRI is used to measure the fiber and laminar orientations. We quantify the performance of DT-MRI and structure tensor (ST) analysis of 3D high resolution MRI in five rat hearts and validate these against manual measurements. The ST and DT data are more similar for measures of the fiber orientation than laminar orientation. The average angle differences of elevation angles are 2.3±27.2˚, R = 0.57 for the fiber, 3.62±36.2˚, R = 0.24 for the laminae and 10.7±37.9˚, R = 0.32 for the laminae normal. The difference between DT and manually measured laminar orientation is 17±15˚ for DT and 5±10˚ for ST. DT and ST are comparable measures of the fiber orientation but ST is a better measure of myolaminar orientation.