Efficient representation of DNA data for pattern recognition using failure factor oracles

  • Authors:
  • Loek Cleophas;Derrick G. Kourie;Bruce W. Watson

  • Affiliations:
  • University of Pretoria, Hatfield, Pretoria, Republic of South Africa;University of Pretoria, Hatfield, Pretoria, Republic of South Africa;University of Pretoria, Hatfield, Pretoria, Republic of South Africa

  • Venue:
  • Proceedings of the South African Institute for Computer Scientists and Information Technologists Conference
  • Year:
  • 2013

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Abstract

In indexing of and pattern matching on DNA sequences, representing all factors of a sequence is important. One efficient, compact representation is the factor oracle (FO). At the same time, any classical deterministic finite automata (DFA) can be transformed to a so-called failure one (FDFA), which may use failure transitions to replace multiple symbol transitions, potentially yielding a more compact representation. We combine the two ideas and directly construct a failure factor oracle (FFO) from a given sequence, in contrast to ex post facto transformation to an FDFA. The algorithm is suitable for long sequences. We empirically compared the resulting FFOs and FOs on number of transitions for many DNA sequences of lengths 4--512, showing gains of up to 10% in total number of transitions, with failure transitions also taking up less space than symbol transitions. Preliminary results on sequence processing runtimes when using FFOs originally showed these to be multiples of those when using FOs, but partial memoization already leads to drastic improvements. Altogether the results are promising, particularly for the use of FFOs for (repeated) factor detection, where recognition speed may be less important than memory use.