The numerical analysis of ordinary differential equations: Runge-Kutta and general linear methods
The numerical analysis of ordinary differential equations: Runge-Kutta and general linear methods
Evolutionary modeling and inference of gene network
Information Sciences—Informatics and Computer Science: An International Journal - Bioinformatics-selected papers from 4th CBGI & 6th JCIS Proceedings
Learning Dynamic Bayesian Networks
Adaptive Processing of Sequences and Data Structures, International Summer School on Neural Networks, "E.R. Caianiello"-Tutorial Lectures
Gene Expression Programming: Mathematical Modeling by an Artificial Intelligence (Studies in Computational Intelligence)
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Mining Class Contrast Functions by Gene Expression Programming
ADMA '09 Proceedings of the 5th International Conference on Advanced Data Mining and Applications
Model gene network by semi-fixed Bayesian network
Expert Systems with Applications: An International Journal
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics - Special issue on game theory
Distance guided classification with gene expression programming
ADMA'06 Proceedings of the Second international conference on Advanced Data Mining and Applications
IEEE Transactions on Signal Processing - Part II
Evolving accurate and compact classification rules with gene expression programming
IEEE Transactions on Evolutionary Computation
IEEE Transactions on Evolutionary Computation
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Gene regulatory networks inference is currently a topic under heavy research in the systems biology field. In this paper, gene regulatory networks are inferred via evolutionary model based on time-series microarray data. A non-linear differential equation model is adopted. Gene expression programming (GEP) is applied to identify the structure of the model and least mean square (LMS) is used to optimize the parameters in ordinary differential equations (ODEs). The proposed work has been first verified by synthetic data with noise-free and noisy time-series data, respectively, and then its effectiveness is confirmed by three real time-series expression datasets. Finally, a gene regulatory network was constructed with 12 Yeast genes. Experimental results demonstrate that our model can improve the prediction accuracy of microarray time-series data effectively.