Development of immunosensor using magnetic nanoparticles and circular microchannels in PDMS

  • Authors:
  • Shailaja Agrawal;Kishore Paknikar;Dhananjay Bodas

  • Affiliations:
  • -;-;-

  • Venue:
  • Microelectronic Engineering
  • Year:
  • 2014

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Abstract

Here we report development of a magnetic nanoparticles based immunosensor chip comprising of specially designed circular microchannel and embedded miniature permanent magnet. The present process of fabrication allows a rapid and reliable tool to create microchannels with ease and at a low cost. The chip permits easy in-flow capture of bacteria, their visual detection and quantification as demonstrated by Escherichia coli detection. Such a technique enhances capture efficiency and makes quantification of captured antigens simple.