Knapsack problems: algorithms and computer implementations
Knapsack problems: algorithms and computer implementations
2-Path Cuts for the Vehicle Routing Problem with Time Windows
Transportation Science
The Shortest-Path Problem with Resource Constraints and k-Cycle Elimination for k ≥ 3
INFORMS Journal on Computing
Subset-Row Inequalities Applied to the Vehicle-Routing Problem with Time Windows
Operations Research
A two-stage vehicle routing model for large-scale bioterrorism emergencies
Networks - Route 2007
A Branch-and-Cut method for the Capacitated Location-Routing Problem
Computers and Operations Research
New Route Relaxation and Pricing Strategies for the Vehicle Routing Problem
Operations Research
An Exact Method for the Capacitated Location-Routing Problem
Operations Research
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We present a model for the optimization of logistics operations in emergency health care systems; in particular, we study the problem of efficient distribution of vaccines or drugs through the simultaneous and coordinated use of distribution centers and vehicles. We devise an exact algorithm based on column generation with three different types of columns and branch-and-bound. The pricing subproblems are solved through advanced dynamic programming techniques. In order to strengthen the dual bounds, we adapt two families of cuts from the literature and we introduce a new one. Our framework also includes primal heuristics and ad-hoc branching rules. An experimental campaign on realistic data proves our method to be effective and flexible.