Computational Modeling for Genetic Splicing Systems

  • Authors:
  • Sam Myo Kim

  • Affiliations:
  • -

  • Venue:
  • SIAM Journal on Computing
  • Year:
  • 1997

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Abstract

A genetic splicing system involves DNA molecules mixed with enzymes and a ligase that allow the molecules to be cleaved and recombined to produce other molecules in addition to the original ones. Recently, using formal language theory, several researchers have investigated the string properties of DNA molecules that may potentially arise from the original set of molecules under the effect of the given restriction enzymes.This paper introduces an algorithm which, given a splicing system whose initial set of strings is regular, constructs a finite state automaton that recognizes the set of DNA molecules spliced by the system. This algorithm solves the open problem of constructing such an automaton and shows a direct approach to the proof of regularity of spliced languages.