3-D Heart Modeling and Motion EstimationBased on Continuous Distance Transform Neural Networks andAffine Transform

  • Authors:
  • Yen-Hao Tseng;Jenq-Neng Hwang;Florence H. Sheehan

  • Affiliations:
  • Information Processing Laboratory, Dept. of Elect. Engr., Box 352500, University of Washington, Seattle, WA 98195, USA;Information Processing Laboratory, Dept. of Elect. Engr., Box 352500, University of Washington, Seattle, WA 98195, USA;Division of Cardiology, School of Medicine, University of Washington, Seattle, WA 98195, USA

  • Venue:
  • Journal of VLSI Signal Processing Systems - special issue on applications of neural networks in biomedical image processing
  • Year:
  • 1998

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Abstract

In this paper, we apply the previously proposedcontinuous distance transform neural network (CDTNN) to represent3-D endocardial (inner) and epicardial (outer) contours andquantitatively estimate the motion of left ventriclesof human hearts from ultrasound images acquired usingtransesophageal echo-cardiography. This CDTNN has many goodproperties as the conventional distance transforms, which aresuitable for 3-D object representation and deformation estimation. We have successfully represented the 3-D epicardia and endocardiaof left ventricles using CDTNNs trained by as few as 7.5% of themanually traced data. The mean absolute error in the testing forone patient over the 27 testing planes were (1.4 ± 1.2 mm)for the endocardium, (1.3 ± 1.0 mm) for the epicardium at end diastole and (1.4 ± 1.2 mm) for theendocardium vs. 1.2 ± 1.0 mm for the epicardium at endsystole. The absolute error measured compares favorably with thehuman inter-observer variability reported for analyzing distances.With this unique distance transform representation that iscontinuous and differentiable, we are also able to systematicallyand effectively measure the amount of 3-D heart motion in terms ofaffine transform.