Genetic subtyping using cluster analysis

Authors:
Tom Burr;James R. Gattiker;Greggory S. LaBerge
Affiliations:
Los Alamos National Laboratory, Los Alamos, NM;Los Alamos National Laboratory, Los Alamos, NM;Denver Police Dept. Crime Lab, Denver, CO and University of Colorado
Venue:
ACM SIGKDD Explorations Newsletter
Year:
2001

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Abstract

In this paper we (1) describe state-of-the-art methods to identify clusters in DNA sequence data for taxonomic analysis; (2) describe a new method with better scaling properties based on model-based clustering, and (3) present examples using the nucleoprotein and hemagglutin regions of influenza and the env and gag regions of human immunodeficiency virus (HIV).