Image Registration for Digital Subtraction Angiography

Authors:
Erik H. W. Meijering;Karel J. Zuiderveld;Max A. Viergever
Affiliations:
Image Sciences Institute, University Hospital Utrecht, HP E01.334, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands. erik@isi.uu.nl;Image Sciences Institute, University Hospital Utrecht, HP E01.334, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands. karel@vitalimages.com;Image Sciences Institute, University Hospital Utrecht, HP E01.334, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands. max@isi.uu.nl
Venue:
International Journal of Computer Vision
Year:
1999

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Abstract

In clinical practice, Digital SubtractionAngiography (DSA) is a powerful technique for the visualization ofblood vessels in the human body. The diagnostic relevance of theimages is often reduced by artifacts which arise from themisalignment of successive images in the sequence, due to patientmotion. In order to improve the quality of the subtraction images,several registration techniques have been proposed. However, becauseof the required computation times, it has never led to algorithmsthat are fast enough so as to be acceptable for integration inclinical applications. In this paper, a new approach to theregistration of digital angiographic images is proposed. It involvesan edge-based selection of control points for which the displacementis computed by means of template matching, and from which thecomplete displacement vector field is constructed by means ofinterpolation. The final warping of the images according to thecalculated displacement vector field is performed real-time bygraphics hardware. Experimental results with several clinical datasets show that the proposed algorithm is both effective and veryfast.