Immune Cognition and Vaccine Strategy: Pathogenic Challenge and Ecological Resilience

Authors:
Rodrick Wallace
Affiliations:
The New York State Psychiatric Institute
Venue:
Open Systems & Information Dynamics
Year:
2002

Citing 0
Cited 2

Toward Cultural Oncology: The Evolutionary Information Dynamics of Cancer

Open Systems & Information Dynamics
Punctuated Equilibrium in Statistical Models of Generalized Coevolutionary Resilience: How Sudden Ecosystem Transitions Can Entrain Both Phenotype Expression and Darwinian Selection

Transactions on Computational Systems Biology IX

Quantified Score

Hi-index	0.00

Visualization

Abstract

We continue to study the implications of IR Cohen's work on immune cognition for vaccine strategies when simple elicitation of sterilizing immunity fails, using a mathematical model derived from the large deviations programme of applied probability. Our work makes explicit the linkage between an individual's 'immunocultural condensation' and embedding social or historical structures and processes, in particular power relations between groups. We use methods adapted from the theory of ecosystem resilience to explore the consequences of the sudden 'perturbation' caused by infection, in the context of such embedding. The methodology open pathways in the design of vaccine strategy which are closed by simplistic genetic or cross-sectional 'inequality' analyses that — in effect — either reify 'race' or deny the persisting burdens of racism.