Vaccination strategies for epidemics in highly mobile populations

  • Authors:
  • Petter Ögren;Clyde F. Martin

  • Affiliations:
  • Department of Mathematics, Division of Optimization and Systems Theory, Royal Institute of Technology, S-10044 Stockholm, Sweden;Department of Mathematics, Institute of Environmental and Human Health, Texas Tech University, Lubbock, TX

  • Venue:
  • Applied Mathematics and Computation
  • Year:
  • 2002

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Abstract

Our goal is to calculate optimal vaccination patterns for a rapidly spreading disease in an urbanized highly mobile population. The goal being to determine if vaccination can effect a disease for which there is low immunity in the population. Different types of structured SIR models are investigated. We construct a model appropriate for a traveling urbanized population and introduce a control in terms of a vaccination program. Linear constraints, a quadratic cost on the control and a linear cost on the number of infected are imposed. In this setting we calculate optimal vaccination patterns using the maximum principle of Pontryagin. The numerics are performed using Matlab.