A qualitative biochemistry and its application to the regulation of the tryptophan operon
Artificial intelligence and molecular biology
Mental leaps: analogy in creative thought
Mental leaps: analogy in creative thought
Knowledge Discovery in Databases
Knowledge Discovery in Databases
Functional representation of designs and redesign problem solving
IJCAI'89 Proceedings of the 11th international joint conference on Artificial intelligence - Volume 2
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A task in the philosophy of discovery is to find reasoning strategies for discovery, which fall into three categories: strategies for generation, evaluation and revision. Because mechanisms are often what is discovered in biology, a newc haracterization of mechanism aids in their discovery. A computational system for discovering mechanisms is sketched, consisting of a simulator, a library of mechanism schemas and components, and a discoverer for generating, evaluating and revising proposed mechanism schemas. Revisions go through stages from how possibly to how plausibly to how actually.