The Application Visualization System: A Computational Environment for Scientific Visualization
IEEE Computer Graphics and Applications
Automating Segmentation of Dual-Echo MR Head Data
IPMI '91 Proceedings of the 12th International Conference on Information Processing in Medical Imaging
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Outputs from a physiologically based toxicokinetic (PB-TK) model for fish were visualized by mapping time series data for specific tissues onto a three dimensional representation of a rainbow trout. The trout representation was generated in stepwise fashion: cross sectional images were obtained from an anesthetized fish using a magnetic resonance imaging (MRI) system; images were processed to classify tissue types; images were stacked and processed to create a three dimensional representation of the fish, encapsulating five volumes corresponding to the liver, kidney, muscle, gastrointestinal tract, and fat. Kinetic data for the disposition of pentachloroethane in trout were generated using a PB-TK model. Model outputs were mapped onto corresponding tissue volumes, representing chemical concentration as color intensity. The visualization was then animated, to show the accumulation of pentachloroethane in each tissue during a continuous branchial (gill) exposure.