Digital Design and Modeling with VHDL and Synthesis
Digital Design and Modeling with VHDL and Synthesis
Hardware designs for local alignment of protein sequences
ISCIS'06 Proceedings of the 21st international conference on Computer and Information Sciences
Microprocessors & Microsystems
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This paper presents the Smith and Waterman Algorithm-Specific ASIC Design (SWASAD) project. This is a hardware solution that implements the S&W algorithm. The SWASAD is an improved implementation of the Biological Information Signal Processor (BISP) design [1], The SWASAD chip fabricated on a 0.5 µ process achieves 3200 million Matrix Cells Per Second (MCPS) per chip, with a layout size of 7.1 mm by 7.1 mm. This is a large improvement over existing designs and improves data throughput by using a smaller datawidth.