Bimodal System for Interactive Indexing and Retrieval of Pathology Images

  • Authors:
  • Dorin Comaniciu;Peter Meer;David Foran;Attila Medl

  • Affiliations:
  • -;-;-;-

  • Venue:
  • WACV '98 Proceedings of the 4th IEEE Workshop on Applications of Computer Vision (WACV'98)
  • Year:
  • 1998

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Abstract

The prototype of a system to assist the physicians in differentialdiagnosis of lymphoproliferative disorders of bloodcells from digitized specimens is presented. The user selectsthe region of interest (ROI) in the image which is thenanalyzed with a fast, robust color segmenter. Queries ina database of validated cases can be formulated in termsof shape (similarity invariant Fourier descriptors), texture(multiresolution simultaneous autoregressive model), color(L*u*v* space), and area, derived from the delineatedROI. The uncertainty of the segmentation process (obtainedthrough a numerical method) determines the accuracy ofshape description (number of Fourier harmonics). Tenfoldcross-validated classification over a database of 261color 640 \times 480 images was implemented to assess the system performance. The ground truth was obtained throughimmunophenotyping by flow cytometry. To provide a naturalman-machine interface, most input commands are bi-modal:either using the mouse or by voice. A speech synthesizerprovides feedback to the user. All the employed computationalmodules are context independent and thus the samesystem can be used in a large variety of application domains.