Protein Structure Prediction by Applying an Evolutionary Algorithm

  • Authors:
  • Richard O. Day;Gary B. Lamont;Ruth Pachter

  • Affiliations:
  • -;-;-

  • Venue:
  • IPDPS '03 Proceedings of the 17th International Symposium on Parallel and Distributed Processing
  • Year:
  • 2003

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Abstract

Interest in protein structure prediction is wide-spread, and has been previously addressed using evolutionary algorithms. In this study we report results of a modified fmGA, which is found to be good at finding semi-optimal solutions in reasonable time. Our study focuses on tuning this fmGA in an attempt to improve the effectiveness and efficiency of the algorithm insolving a protein structure and in finding better ways to identify secondary structures. Problem definition, protein model representation, mapping to algorithm domain, tool selection modifications and conducted experiments are discussed