Application of cover-free codes and combinatorial designs to two-stage testing

  • Authors:
  • Toby Berger;Vladimir I. Levenshtein

  • Affiliations:
  • School of Electrical Engineering, Cornell University, Ithaca, NY;Keldysh Institute for Applied Mathematics, Russian Academy of Sciences, Miusskaya sq. 4, 125047, Moscow, Russia

  • Venue:
  • Discrete Applied Mathematics - Special issue: International workshop on coding and cryptography (WCC 2001)
  • Year:
  • 2003

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Abstract

We study combinatorial and probabilistic properties of cover-free codes and block designs which are useful for their efficient application as the first stage of two-stage group testing procedures. Particular attention is paid to these procedures because of their importance in such applications as monoclonal antibody generation and cDNA library screening.