Application-level scheduling on distributed heterogeneous networks
Supercomputing '96 Proceedings of the 1996 ACM/IEEE conference on Supercomputing
Implementing a performance forecasting system for metacomputing: the Network Weather Service
SC '97 Proceedings of the 1997 ACM/IEEE conference on Supercomputing
Proceedings of the conference on Visualization '01
From Sinograms to Surfaces: A Direct Approach to the Segmentation of Tomographic Data
MICCAI '01 Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention
The SDSC storage resource broker
CASCON '98 Proceedings of the 1998 conference of the Centre for Advanced Studies on Collaborative research
HCW '00 Proceedings of the 9th Heterogeneous Computing Workshop
The GridPort Toolkit: A System for Building Grid Portals
HPDC '01 Proceedings of the 10th IEEE International Symposium on High Performance Distributed Computing
Global telescience featuring IPv6 at iGrid2002
Future Generation Computer Systems - iGrid 2002
Grid resource management
Journal of Parallel and Distributed Computing
Real-time multi-scale brain data acquisition, assembly, and analysis using an end-to-end OptIPuter
Future Generation Computer Systems - IGrid 2005: The global lambda integrated facility
Computers in Biology and Medicine
Electron tomography of complex biological specimens on the Grid
Future Generation Computer Systems
Grid enabled magnetic resonance scanners for near real-time medical image processing
Journal of Parallel and Distributed Computing
An efficient and transparent transaction management based on the data workflow of HVEM DataGrid
CLADE '08 Proceedings of the 6th international workshop on Challenges of large applications in distributed environments
Web enabling desktop workflow applications
Proceedings of the 4th Workshop on Workflows in Support of Large-Scale Science
GCCB'06 Proceedings of the 2006 international conference on Distributed, high-performance and grid computing in computational biology
International Journal of High Performance Computing Applications
Object reuse and exchange for publishing and sharing workflows
Proceedings of the 6th workshop on Workflows in support of large-scale science
A performance prediction model for tomographic reconstruction in structural biology
VECPAR'04 Proceedings of the 6th international conference on High Performance Computing for Computational Science
Interdisciplinary innovation in international initiatives
Transactions on Computational Systems Biology IV
Bundle and Pool Architecture for Multi-Language, Robust, Scalable Workflow Executions
Journal of Grid Computing
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Electron tomography is a powerful tool for deriving three-dimensional (3D) structural information about biological systems within the spatial scale spanning 1 nm3 and 10 µm3. With this technique, it is possible to derive detailed models of subcellular components such as organelles and synaptic complexes and to resolve the 3D distribution of their protein constituents in situ. While there continues to be progress towards the integration of high-performance computing technologies with traditional electron tomography processes, there is a significant need for more transparent integration with applications and to minimize the administrative overhead and complexity (resource administration, authentication, scheduling, data delivery) passed on to the noncomputer scientist end user. Here we present the "Telescience Portal" (https://gridport.npaci.edu/Telescience) as an example of a fully integrated, web-based solution for performing end-to-end electron tomography. More than just a collection of individual applications, the Portal provides a transparent workflow, where simple intuitive interfaces for grid-enabled parallel computation, resource scheduling, remote instrumentation, advanced image processing and visualization, access to distributed/federated databases, and network-enabled data management and archival are tightly coupled within a secure environment which promotes increased collaboration between researchers. This tightly integrated Telescience system is a test-bed application for using grid resources to accelerate the throughput of data acquisition and processing, increase access to scarce and/or expensive instrumentation, and improve the accuracy of derived data products.