Methods in Neuronal Modeling: From synapses to networks
Methods in Neuronal Modeling: From synapses to networks
Neural Networks: A Comprehensive Foundation
Neural Networks: A Comprehensive Foundation
Pulsed Neural Networks
Spiking Neuron Models: An Introduction
Spiking Neuron Models: An Introduction
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Understanding information processing at the neuronal level would provide valuable insights to computational intelligence research and computational neuroscience. In particular, understanding constraints on neuronal spike trains would provide indication about the type of syntactic rules used by neurons when processing information. A recent discovery, reported here, was made through analyzing microelectrode recordings (MER) made during surgical procedure in humans. Analysis of MERs of extracellular neuronal activity has gained increasing interest due to potential improvements to surgical techniques involving ablation or placement of deep brain stimulators, done in the treatment of advanced Parkinson's disease. Important to these procedures is the identification of different brain structures such as the globus pallidus internus from the spike train being recorded from the intracranial probe tip during surgery. Spike train data gathered during surgical procedure from multiple patients were processed using a novel feature extraction method reported here. Distinct structures within the spike trains were identified and used to build an effective brain region classifier. The extracted features upon analysis provide some insight into the 'syntactic' constraint on spike trains.