Building Three-Dimensional Ribonucleic Acid Structures

  • Authors:
  • François Major

  • Affiliations:
  • -

  • Venue:
  • Computing in Science and Engineering
  • Year:
  • 2003

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Abstract

MC-Sym is an intelligent computer system that builds 3D ribonucleic acid structures from low-resolution data by combining symbolic and numerical computations. Specifically, the symbolic step generates all-atom sketches of 3D structures that nonlinear optimization methods can refine in a second step.