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Biological, chemical, and radiological agents cantamper with the activities of medical care providers, patientsamples, and medicine administration. This results in a shutdown of all medical care, leaving patients at a major risk. Thetechnical challenge is to develop sensors to detect and monitorany violations in the medical care environment before threat tolife occurs. Wireless devices must communicate multimedia datasuch as patient information, laboratory results, prescriptions,and X-ray and EKG reports. The reliability, security, andaccuracy of these sensors and wireless devices can affect thetimeliness access to information for patient monitoring. Inaddition, data can be corrupted, computer information systemscan fail, and communication networks may experience denial ofservice attacks leading to complete failure of proper patient care.In this paper, we discuss security and safety issues in medicalenvironment, the technology, types, and characteristics ofsensors, and research issues in smart antennas, denial of service,fault tolerant authentication, privacy issues, and energyconsiderations. A discussion of sensors in patient rooms,clinics/wards, hospitals, and measurements of safety and securityis presented. The available devices for sensor and wirelesscommunication are also briefly included.