Fast Intensity-based 2D-3D Image Registration of Clinical Data Using Light Fields

  • Authors:
  • Daniel B. Russakoff;Torsten Rohlfing;Calvin R. Maurer, Jr.

  • Affiliations:
  • -;-;-

  • Venue:
  • ICCV '03 Proceedings of the Ninth IEEE International Conference on Computer Vision - Volume 2
  • Year:
  • 2003

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Abstract

Registration of a preoperative CT (3D) image to one or more X-rayprojection (2D) images, a special case of the pose estimationproblem, has been attempted in a variety of ways with varyingdegrees of success. Recently, there has been a great deal ofinterest in intensity-based methods. One of the drawbacks to suchmethods is the need to create digitally reconstructed radiographs(DRRs) at each step of the optimization process. DRRs are typicallygenerated by ray casting, an operation that requires O(n3) time,where we assume that n is approximately the size (in voxels) of oneside of the DRR as well as one side of the CT volume. We addressthis issue by extending light field rendering techniques from thecomputer graphics community to generate DRRs instead ofconventional rendered images. Using light fields allows most of thecomputation to be performed in a preprocessing step; after thisprecomputation, very accurate DRRs can be generated in O(n2) time.Another important issue for 2D-3D registration algorithms isvalidation. Previously reported 2D-3D registration algorithms werevalidated using synthetic data or phantoms but not clinical data.We present an intensity-based 2D-3D registration system thatgenerates DRRs using light fields; we validate its performanceusing clinical data with a known gold standard transformation.