Synthetic PET imaging for grasping: from primate Neurophysiology to human behavior

  • Authors:
  • Michael A. Arbib;Andrew H. Fagg;Scott T. Grafton

  • Affiliations:
  • USC Brain Project, University of Southern California Los Angeles, California;Computer Science Department, University of Massachusetts, Amherst, MA;Dartmouth College, Hanover, NH

  • Venue:
  • Exploratory analysis and data modeling in functional neuroimaging
  • Year:
  • 2003

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Abstract

Synthetic PET imaging is a technique for using computational models derived from primate neurophysiological data to predict and analyze the results of human PET studies. This technique makes use of the hypothesis that is correlated with the integrated synaptic activity in a localized brain region. In this chapter, we describe the Synthetic PET imaging approach, and demonstrate how it is applied to the FARS model to parietal-premotor interactions underlying primate grasp control. The Synthetic PET measures are interactions underlying primate grasp control. The Synthetic PET measures are computed for a simulated conditional/non-coditional grasping experiment, and then compared to the results of a similar human PET study. We then show how the human PET results may be used to further constrain the computational model.