Similarity measures of RNA structures

  • Authors:
  • Tamas Horvath

  • Affiliations:
  • GMD - SET.KI, Schloss Birlinghoven, Sankt Augustin, Germany

  • Venue:
  • ACM SIGBIO Newsletter - Special issue on biomedical applications of knowledge discovery in databases
  • Year:
  • 1998

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Abstract

Untranslated regions of (pre-) mRNAs contain regulatory elements called signal structures to control gene expression at the posttranscriptional level. Their regulatory information is encoded in their primary and secondary structures. Given a set of known signal structures belonging to several classes, our aim is to find a) the presence of signal structures belonging to known classes on uncharacterized mRNA, and b) uncharacterized signal structure classes. We have applied relational instance-based method for the first problem.