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The Workshop on Science of Design for Information Systems (SDIS2003) was held in Seattle, September 16 and 17, 2003. It was funded through a grant from the National Science Foundation2, with the goal of assessing the state-of-the-art in information systems design and suggesting promising directions for future research and development in this critical area.This short report is intended to provide an overview of the workshop report for the SIGMOD audience. In summary, we believe that there is a need to develop a new set of methodologies for information system design that cover advanced aspects of such systems. In particular, we are interested in techniques that offer guidance in the design of information systems that integrate data from multiple sources, handle dynamic aspects of the system (e.g., rapidly changing data, tracking provenance, version management), include aspects influenced by data location (e.g., cached objects and queries, peer-to-peer data sharing), model process-oriented issues (e.g., workflows, web-services), and account for the security and privacy of the data. AB@The interested reader can find a full version of this report at the workshop website, www.cs.wisc.edu/sdis03.