Machine Learning
Interpreting microarray expression data using text annotating the genes
Information Sciences—Applications: An International Journal
Using Multiple Levels of Learning and Diverse Evidence to Uncover Coordinately Controlled Genes
ICML '00 Proceedings of the Seventeenth International Conference on Machine Learning
Modeling belief in dynamic systems part II: revision and update
Journal of Artificial Intelligence Research
Biological applications of multi-relational data mining
ACM SIGKDD Explorations Newsletter
A Feature Selection Newton Method for Support Vector Machine Classification
Computational Optimization and Applications
Induction of comprehensible models for gene expression datasets by subgroup discovery methodology
Journal of Biomedical Informatics - Special issue: Biomedical machine learning
The Journal of Machine Learning Research
Detection of Gene Expressions in Microarrays by Applying Iteratively Elastic Neural Net
ICANNGA '07 Proceedings of the 8th international conference on Adaptive and Natural Computing Algorithms, Part II
Matrix Metric Adaptation Linear Discriminant Analysis of Biomedical Data
IWANN '09 Proceedings of the 10th International Work-Conference on Artificial Neural Networks: Part I: Bio-Inspired Systems: Computational and Ambient Intelligence
EA'09 Proceedings of the 9th international conference on Artificial evolution
Qualitative reasoning on systematic gene perturbation experiments
CIBB'10 Proceedings of the 7th international conference on Computational intelligence methods for bioinformatics and biostatistics
An ensemble of case-based classifiers for high-dimensional biological domains
ICCBR'05 Proceedings of the 6th international conference on Case-Based Reasoning Research and Development
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Gene-expression microarrays, commonly called gene chips, make it possible to simultaneously measure the rate at which a cell or tissue is expressing--translating into a protein--each of its thousands of genes. One can use these comprehensive snapshots of biological activity to infer regulatory pathways in cells; identify novel targets for drug design; and improve the diagnosis, prognosis, and treatment planning for those suffering from disease. However, the amount of data this new technology produces is more than one can manually analyze. Hence, the need for automated analysis of microarray data offers an opportunity for machine learning to have a significant impact on biology and medicine. This article describes microarray technology, the data it produces, and the types of machine learning tasks that naturally arise with these data. It also reviews some of the recent prominent applications of machine learning to gene-chip data, points to related tasks where machine learn-Lug might have a further impact on biology and medicine, and describes additional types of interesting data that recent advances in biotechnology allow biomedical researchers to collect.