An agent- and ontology-based system for integrating public gene, protein, and disease databases
Journal of Biomedical Informatics
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After the completion of the Human GenomeProject, a new, post genomic era, is beginning toanalyze and interpret the huge amount of genomicinformation. Information methods and techniquesfrom areas such as database integration, informationretrieval, knowledge discovery in databases (KDD)and decision support systems (DSS) are needed. Thesesystems should take into account idiosyncraticdifferences between these two interacting fields,medicine and biology. Their correspondent medicalinformatics (MI) and bioinformatics (BI) should alsointeract and there is a need for a point to support thecommunication. Biomedical ontologies can be used toenhance biomedical information systems, providing aknowledge sharing framework. However, ontologytools are still in its infancy and there is a need ofstandards, services, automatic management tools,etc... to be able to properly apply this technologyenvironment. Nevertheless, ontologies are just thetechnical framework the most important issue is thecontent and the use policy.