Independent component analysis minimizing convex divergence
ICANN/ICONIP'03 Proceedings of the 2003 joint international conference on Artificial neural networks and neural information processing
IEEE Transactions on Systems, Man, and Cybernetics, Part C: Applications and Reviews
The α-EM algorithm: surrogate likelihood maximization using α-logarithmic information measures
IEEE Transactions on Information Theory
Research Article: Search of regular sequences in promoters from eukaryotic genomes
Computational Biology and Chemistry
Statistical feature selection from chaos game representation for promoter recognition
ICCS'06 Proceedings of the 6th international conference on Computational Science - Volume Part II
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A new method for E. coli DNA segment classification on promoters and non-promoters is presented. The algorithm is based on the Independent Component Analysis (ICA). Since the DNA segments are composed of discrete symbols, this paper contains two major steps: (1) Position-dependent transformation of DNA segments to real number sequences, and (2) Applications of the ICA to the E. coli promoter recognition. These steps are related to each other. Therefore, algorithmic explanations are given in detail while referring mutually. The automatic precision of 93.7% is obtained. Since the presented method allows threshold adjustments, twilight-zone data can be further cross-checked individually so that false negatives are reduced.