Comparing 3D Protein Structures Similarity by Using Fractal Features

Authors:
Chenyang Cui;Donghui Wang;Jiaoying Shi
Affiliations:
Zhejiang University;Zhejiang University;Zhejiang University
Venue:
CSB '04 Proceedings of the 2004 IEEE Computational Systems Bioinformatics Conference
Year:
2004

Citing 2
Cited 1

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Efficient Approaches for Retrieving Protein Tertiary Structures

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Abstract

In this paper, we propose a new method for finding similarity in 3-D protein structure comparison. Different from the other existing methods, our method is grounded in the theory of fractal geometry. The proposed feature vectors of protein structures are simple to implement . The method is very fast because it requires neither alignment of the chains nor any chain-chain comparison. We calculate the fractal features of a set of 200 protein structures selected from PDB(Protein Data Bank). The experimental result shows that our method is very effective in classification of 3-D protein structures.