DAML+OIL: A Reason-able Web Ontology Language
EDBT '02 Proceedings of the 8th International Conference on Extending Database Technology: Advances in Database Technology
Exploring social annotations for the semantic web
Proceedings of the 15th international conference on World Wide Web
Granularity, scale and collectivity: when size does and does not matter
Journal of Biomedical Informatics - Special issue: Biomedical ontologies
Journal of Biomedical Informatics
Exploiting Gene Ontology to Conceptualize Biomedical Document Collections
ASWC '08 Proceedings of the 3rd Asian Semantic Web Conference on The Semantic Web
Applied Ontology - Towards a Metaontology for the Biomedical Domain
The Knowledge Engineering Review
A little semantic web goes a long way in biology
ISWC'05 Proceedings of the 4th international conference on The Semantic Web
The OWL instance store: system description
CADE' 20 Proceedings of the 20th international conference on Automated Deduction
Applied Ontology - Towards a Metaontology for the Biomedical Domain
GOtoGene: a method for determining the functional similarity among gene products
AusDM '12 Proceedings of the Tenth Australasian Data Mining Conference - Volume 134
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High-quality annotation of biological data is central to bioinformatics. Annotation using terms from ontologies provides reliable computational access to data. The Gene Ontology (GO), a structured controlled vocabulary of nearly 17,000 terms, is becoming the de facto standard for describing the functionality of gene products. Many prominent biomedical databases use GO as a source of terms for functional annotation of their gene-product entries to promote consistent querying and interoperability. However, current annotation editors do not constrain the choice of GO terms users may enter for a given gene product, potentially resulting in an inconsistent or even nonsensical description. Furthermore, the process of annotation is largely an unguided one in which the user must wade through large GO subtrees in search of terms. Relying upon a reasoner loaded with a DAML+OIL version of GO and an instance store of mined GO-term-to-GO-term associations, GOAT aims to aid the user in the annotation of gene products with GO terms by displaying those field values that are most likely to be appropriate based on previously entered terms. This can result in a reduction in biologically inconsistent combinations of GO terms and a less tedious annotation process on the part of the user.