A method of estimation of magnetic resonance spectroscopy using complex-valued neural networks

  • Authors:
  • Naoyuki Morita;Osamu Konishi

  • Affiliations:
  • Department of Medical Technology, Kochi Gakuen College, Kochi, 780-0955 Japan;Department of Complex Systems, Future University, Hakodate, 041-8655 Japan

  • Venue:
  • Systems and Computers in Japan
  • Year:
  • 2004

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Abstract

MRS (magnetic resonance spectroscopy) consists of collecting the nuclear magnetic resonance (NMR) spectrum of the metabolites in the living body and estimating it. In the field of MRS, we usually get an NMR spectrum by applying the Fourier transform to the real part of the NMR signal [free induction decay (FID) signal], which is a complex-valued signal. We must then measure the area of the spectral peak to estimate metabolites in the living body from the spectrum. A curve fitting technique is used for that measurement. However, this technique is not suitable for large quantities of data processing, because human intervention is necessary and is laborious. For this reason, an automatic method of estimating an NMR spectrum is required in the field of MRS. In this paper, we propose a method of estimation of an NMR spectrum by using a Hopfield complex-valued neural network and try to estimate the spectrum automatically. In addition, we consider damping state of the NMR signal and devise a method called sequential extension of section (SES). It is shown that the estimation precision of the spectrum improves when SES is used. Furthermore, SES is found to reduce the local minimum problem in Hopfield neural networks. © 2004 Wiley Periodicals, Inc. Syst Comp Jpn, 35(10): 14–22, 2004; Published online in Wiley InterScience (). DOI 10.1002/scj.10705