Linear-time algorithms for computing maximum-density sequence segments with bioinformatics applications

  • Authors:
  • Michael H. Goldwasser;Ming-Yang Kao;Hsueh-I Lu

  • Affiliations:
  • Department of Mathematics and Computer Science, Saint Louis University, 221 N. Grand Blvd, St. Louis, MO 63103-2007, USA;Department of Computer Science, Northwestern University, Evanston, IL 60201, USA;Institute of Information Science, Academia Sinica, 128 Academia Road, Section 2, Taipei 115, Taiwan and Department of Computer Science and Information Engineering, National Taiwan University, Taip ...

  • Venue:
  • Journal of Computer and System Sciences
  • Year:
  • 2005

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Abstract

We study an abstract optimization problem arising from biomolecular sequence analysis. For a sequence A of pairs (a"i,w"i) for i=1,...,n and w"i0, a segmentA(i,j) is a consecutive subsequence of A starting with index i and ending with index j. The width of A(i,j) is w(i,j)=@?"i"=