Design patterns: elements of reusable object-oriented software
Design patterns: elements of reusable object-oriented software
The grid: blueprint for a new computing infrastructure
The grid: blueprint for a new computing infrastructure
Building application frameworks: object-oriented foundations of framework design
Building application frameworks: object-oriented foundations of framework design
Framelets—small and loosely coupled frameworks
ACM Computing Surveys (CSUR)
Event Filtering Framework: Key Criteria and Design Trade-offs
COMPSAC '97 Proceedings of the 21st International Computer Software and Applications Conference
Grids and grid technologies for wide-area distributed computing
Software—Practice & Experience
The Anatomy of the Grid: Enabling Scalable Virtual Organizations
CCGRID '01 Proceedings of the 1st International Symposium on Cluster Computing and the Grid
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Bioinformatics is an area that demands the management of large amounts of data. One example is Computer Assisted Drug Design (CADD) where it is necessary to organize the results of a large number of protein-ligand interaction simulations. Projects such as The United Devices Cancer Research Project, The Smallpox Grid Project and FightAIDS@home use grid computing to gather results from a large number of computers. These projects, nonetheless, have particular solutions, developed by commercial companies, to distribute and rank the results. Due to the need for handling large amounts of data in specific formats, this work presents a framework dedicated to handling biological data with a case study on CADD. To validate the implementation, an open source approach was employed using the XtremWeb platform to distribute the tasks, and the software AutoDock 3.0 for simulating protein-ligand interactions. The XtremWeb dispatcher was adapted to call the proposed result handling framework, which analyzes the results from the protein-ligand interaction outputs in order to extract and organize the relevant information.