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This paper uses estimated model parameters as inputs into multivariate quality control charts. The thickness of paper leaving a paper mill is measured at a high sampling rate, and these data are grouped into successive data segments. A stochastic model for paper is fitted to each data segment, leading to parameter estimates and information-based standard errors for these estimates. The estimated model parameters vary by more than one can be explained by the information-based standard errors, suggesting that the ‘true’ underlying parameters are not constant over time. A model is formulated for the true parameters in which the information matrix dictates the distribution for the observed parameters given the true parameters. Copyright © 2004 John Wiley & Sons, Ltd.