Biomedical Informatics Research Network: Integrating Multi-Site Neuroimaging Data Acquisition, Data Sharing and Brain Morphometric Processing

Authors:
Jorge Jovicich;Carey Priebe;Michael M. Miller;Randy Buckner;Bruce Rosen
Affiliations:
Massachusetts General Hospital;Johns Hopkins University;Johns Hopkins University;Howard Hughes Medical Institute;Massachusetts General Hospital
Venue:
CBMS '05 Proceedings of the 18th IEEE Symposium on Computer-Based Medical Systems
Year:
2005

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Abstract

The Biomedical Informatics Research Network (BIRN) is a National Institutes of Health (USA) initiative that fosters distributed collaborations in biomedical science by utilizing information technology innovations. Morphometry BIRN is one of its testbeds and has the goal to develop the ability to conduct clinical imaging studies across multiple sites, to analyze structural imaging data with the most powerful software regardless of development site, and to test new hypotheses on large collections of subjects with well-characterized image and clinical data. Through large-scale analyses of patient population data acquired and pooled across sites, we are investigating neuroanatomic correlates of Alzheimerýs Disease Depression and Mild Cognitive Impairment subjects. This paper describes progress in multi-site image calibration and in software integration for multi-site image processing.