System-level design automation tools for digital microfluidic biochips

  • Authors:
  • Krishnendu Chakrabarty;Fei Su

  • Affiliations:
  • Duke University, Durham, NC;Duke University, Durham, NC

  • Venue:
  • CODES+ISSS '05 Proceedings of the 3rd IEEE/ACM/IFIP international conference on Hardware/software codesign and system synthesis
  • Year:
  • 2005

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Abstract

Biochips based on digital microfluidics offer a powerful platform for massively parallel biochemical analysis such as clinical diagnosis and DNA sequencing. Current full-custom design techniques for digital microfluidic biochips do not scale well for increasing levels of system integration. Analogous to classical VLSI synthesis, a top-down system-level design automation approach can shorten the biochip design cycle and reduce human effort. We present here an overview of a system-level design methodology that includes architectural synthesis and physical design. The proposed design automation approach is expected to relieve biochip users from the burden of manual optimization of bioassays, time-consuming hardware design, and costly testing and maintenance procedures.