Using Global Optimization for a Microparticle Identification Problem with Noisy Data

  • Authors:
  • M. C. Bartholomew-Biggs;Z. J. Ulanowski;S. Zakovic

  • Affiliations:
  • Numerical Optimization Centre, University of Hertfordshire, Herts, UK AL10 9AB;STRC, University of Hertfordshire, Herts, UK AL10 9AB;Department of Computing, Imperial College, London

  • Venue:
  • Journal of Global Optimization
  • Year:
  • 2005

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Abstract

We report some experience with optimization methods applied to an inverse light scattering problem for spherical, homogeneous particles. Such particles can be identified from experimental data using a least squares global optimization method. However, if there is significant noise in the data, the "best" solution may not correspond well to the "actual" particle. We suggest a way in which the original least squares solution may be improved by using a constrained optimization calculation which considers the position of peaks in the data. This approach is applied first to multi-angle data with varying amounts of artificially introduced noise and then to examples of single-particle experimental data patterns characterized by high noise levels.