Some refinements of rough k-means clustering
Pattern Recognition
A Comparison of Fuzzy Clustering Approaches for Quantification of Microarray Gene Expression
Journal of Signal Processing Systems
Evolutionary fuzzy cluster analysis with Bayesian validation of gene expression profiles
Journal of Intelligent & Fuzzy Systems: Applications in Engineering and Technology - Evolutionary computation in bioinformatics
Alternative adaptive fuzzy C-means clustering
EC'06 Proceedings of the 7th WSEAS International Conference on Evolutionary Computing
Fuzzy c-means clustering with prior biological knowledge
Journal of Biomedical Informatics
FPF-SB: a scalable algorithm for microarray gene expression data clustering
ICDHM'07 Proceedings of the 1st international conference on Digital human modeling
Fuzzy clustering of time series in the frequency domain
Information Sciences: an International Journal
ICANN'06 Proceedings of the 16th international conference on Artificial Neural Networks - Volume Part II
Rough-Fuzzy Clustering for Grouping Functionally Similar Genes from Microarray Data
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
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Motivation: In the interpretation of gene expression data from a group of microarray experiments that include samples from either different patients or conditions, special consideration must be given to the pleiotropic and epistatic roles of genes, as observed in the variation of gene coexpression patterns. Crisp clustering methods assign each gene to one cluster, thereby omitting information about the multiple roles of genes. Results: Here, we present the application of a local search heuristic, Fuzzy J-Means, embedded into the variable neighborhood search metaheuristic for the clustering of microarray gene expression data. We show that for all the datasets studied this algorithm outperforms the standard Fuzzy C-Means heuristic. Different methods for the utilization of cluster membership information in determining gene coregulation are presented. The clustering and data analyses were performed on simulated datasets as well as experimental cDNA microarray data for breast cancer and human blood from the Stanford Microarray Database. Availability: The source code of the clustering software (C programming language) is freely available from Nabil.Belacel@nrc-cnrc.gc.ca