SARGE: a tool for creation of putative genetic networks

Authors:
O. J. Shaw;C. Harwood;L. J. Steggles;A. Wipat
Affiliations:
School of Computing Science, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, UK;School of Cell and Molecular Biosciences, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK;School of Computing Science, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, UK;School of Computing Science, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, UK
Venue:
Bioinformatics
Year:
2004

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Cited 1

Modelling and analysing genetic networks: from boolean networks to petri nets

CMSB'06 Proceedings of the 2006 international conference on Computational Methods in Systems Biology

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Abstract

Summary: SARGE is a tool for creating, visualizing and manipulating a putative genetic network from time series microarray data. The tool assigns potential edges through time-lagged correlation, incorporates a clustering mechanism, an interactive visual graph representation and employs simulated annealing for network optimization. Availability: The application is available as a .jar file from http://www.bioinformatics.cs.ncl.ac.uk/sarge/index.html