Finding the population variance of costs over the solution space of the TSP in polynomial time
MATH'07 Proceedings of the 11th WSEAS International Conference on Applied Mathematics
Multilocus consensus genetic maps (MCGM): Formulation, algorithms, and results
Computational Biology and Chemistry
Efficient and accurate construction of genetic linkage maps from noisy and missing genotyping data
WABI'07 Proceedings of the 7th international conference on Algorithms in Bioinformatics
A fast and scalable clustering-based approach for constructing reliable radiation hybrid maps
Proceedings of the 12th International Workshop on Data Mining in Bioinformatics
Radiation hybrid map construction problem parameterized
Journal of Combinatorial Optimization
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Summary: Carhta Gene: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. Carhta Gene: performs multipoint maximum likelihood estimations with accelerated expectation--maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. Carhta Gene: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated. Availability: The program is available free of charge from www.inra.fr/bia/T/CarthaGene for Linux, Windows and Solaris machines (with Open Source). Contact: tschiex@toulouse.inra.fr