Carhta Gene: multipopulation integrated genetic and radiation hybrid mapping

  • Authors:
  • Simon De Givry;Martin Bouchez;Patrick Chabrier;Denis Milan;Thomas Schiex

  • Affiliations:
  • INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France;INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France;INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France;INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France;INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France

  • Venue:
  • Bioinformatics
  • Year:
  • 2005

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Abstract

Summary: Carhta Gene: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. Carhta Gene: performs multipoint maximum likelihood estimations with accelerated expectation--maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. Carhta Gene: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated. Availability: The program is available free of charge from www.inra.fr/bia/T/CarthaGene for Linux, Windows and Solaris machines (with Open Source). Contact: tschiex@toulouse.inra.fr