The Graphical Query Language: a tool for analysis of gene expression time-courses

Authors:
Ivan G. Costa;Alexander Schönhuth;Alexander Schliep
Affiliations:
Max Planck Institute for Molecular Genetics, Department of Computational Molecular Biology Ihnestrasse 73, 14195 Berlin, Germany;Center for Applied Computer Science, University of Cologne Weyertal 80, 50937 Cologne, Germany;Max Planck Institute for Molecular Genetics, Department of Computational Molecular Biology Ihnestrasse 73, 14195 Berlin, Germany
Venue:
Bioinformatics
Year:
2005

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Abstract

Summary: The Graphical Query Language (GQL) is a set of tools for the analysis of gene expression time-courses. They allow a user to pre-process the data, to query it for interesting patterns, to perform model-based clustering or mixture estimation, to include subsequent refinements of clusters and, finally, to use other biological resources to evaluate the results. Analyses are carried out in a graphical and interactive environment, allowing expert intervention in all stages of the data analysis. Availability: The GQL package is freely available under the GNU general public license (GPL) at http://www.ghmm.org/gql Contact: schliep@molgen.mpg.de