Partition-distance via the assignment problem

  • Authors:
  • Dmitry A. Konovalov;Bruce Litow;Nigel Bajema

  • Affiliations:
  • School of Information Technology, James Cook University Townsville, QLD 4811, Australia;School of Information Technology, James Cook University Townsville, QLD 4811, Australia;School of Information Technology, James Cook University Townsville, QLD 4811, Australia

  • Venue:
  • Bioinformatics
  • Year:
  • 2005

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Abstract

Motivation: Accuracy testing of various pedigree reconstruction methods requires an efficient algorithm for the calculation of distance between a known partition and its reconstruction. The currently used algorithm of Almudevar and Field takes a prohibitively long time for certain partitions and population sizes. Results: We present an algorithm that very efficiently reduces the partition-distance calculation to the classic assignment problem of weighted bipartite graphs that has known polynomial-time solutions. The performance of the algorithm is tested against the Almudevar and Field partition-distance algorithm to verify the significant improvement in speed. Availability: Computer code written in java is available upon request from the first author. Contact: dmitry.konovalov@jcu.edu.au