Neuroscience instrumentation and distributed analysis of brain activity data: a case for eScience on global Grids: Research Articles

Authors:
Rajkumar Buyya;Susumu Date;Yuko Mizuno-Matsumoto;Srikumar Venugopal;David Abramson
Affiliations:
Grid Computing and Distributed Systems (GRIDS) Laboratory, Department of Computer Science and Software Engineering, The University of Melbourne, Australia;Graduate School of Information Science and Technology, Department of Bioinformatics Engineering, Osaka University, Japan;Department of Information Systems Engineering, Graduate School of Osaka University, Japan;Grid Computing and Distributed Systems (GRIDS) Laboratory, Department of Computer Science and Software Engineering, The University of Melbourne, Australia;School of Computer Science and Software Engineering, Monash University, Melbourne, Australia
Venue:
Concurrency and Computation: Practice & Experience
Year:
2005

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Abstract

The distribution of knowledge (by scientists) and data sources (advanced scientific instruments), and the need for large-scale computational resources for analyzing massive scientific data are two major problems commonly observed in scientific disciplines. Two popular scientific disciplines of this nature are brain science and high-energy physics. The analysis of brain-activity data gathered from the MEG (magnetoencephalography) instrument is an important research topic in medical science since it helps doctors in identifying symptoms of diseases. The data needs to be analyzed exhaustively to efficiently diagnose and analyze brain functions and requires access to large-scale computational resources. The potential platform for solving such resource intensive applications is the Grid. This paper presents the design and development of MEG data analysis system by leveraging Grid technologies, primarily Nimrod-G, Gridbus, and Globus. It describes the composition of the neuroscience (brain-activity analysis) application as parameter-sweep application and its on-demand deployment on global Grids for distributed execution. The results of economic-based scheduling of analysis jobs for three different optimizations scenarios on the world-wide Grid testbed resources are presented along with their graphical visualization. Copyright © 2005 John Wiley & Sons, Ltd.