Computer as Thinker/Doer: Problem-Solving Environments for Computational Science
IEEE Computational Science & Engineering
Component Based Problem Solving Environment
Euro-Par '02 Proceedings of the 8th International Euro-Par Conference on Parallel Processing
Designing Grid-based Problem Solving Environments and Portals
HICSS '01 Proceedings of the 34th Annual Hawaii International Conference on System Sciences ( HICSS-34)-Volume 9 - Volume 9
Towards a truly integrated enterprise modeling and analysis environment
Computers in Industry
WebBlow: a Web/agent-based multidisciplinary design optimization environment
Computers in Industry - Special issue: Knowledge sharing in collaborative design environments
Using Web services to integrate heterogeneous simulations in a grid environment
Future Generation Computer Systems
Building problem-solving environments with application web service toolkits
Future Generation Computer Systems - Special section: Complex problem-solving environments for grid computing
Optimizing Chemotherapy Scheduling Using Local Search Heuristics
Operations Research
Heuristic design of cancer chemotherapies
IEEE Transactions on Evolutionary Computation
Automating the drug scheduling of cancer chemotherapy via evolutionary computation
Artificial Intelligence in Medicine
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This paper presents a medical problem solving environment (PSE) designed for modelling, simulation, and optimisation of clinical cancer chemotherapy. In order to find optimal chemotherapeutic treatments, two population-based evolutionary algorithms -- Genetic Algorithms and Particle Swarm Optimisation -- have been applied, which can use web services and grid computing to evaluate potential solutions in a distributed and customizable manner. The versatility and robustness of these algorithms make the suggested problem solving environment scalable and adaptable to other problem domains.