Noise adaptation in integrate-and-fire neurons
Neural Computation
An equivalence between sparse approximation and support vector machines
Neural Computation
Bayesian Classification With Gaussian Processes
IEEE Transactions on Pattern Analysis and Machine Intelligence
An introduction to support Vector Machines: and other kernel-based learning methods
An introduction to support Vector Machines: and other kernel-based learning methods
Numerical Recipes in C: The Art of Scientific Computing
Numerical Recipes in C: The Art of Scientific Computing
Dynamics of the firing probability of noisy integrate-and-fire neurons
Neural Computation
What causes a Neuron to spike?
Neural Computation
Firing rate of the noisy quadratic integrate-and-fire neuron
Neural Computation
Sparse bayesian learning and the relevance vector machine
The Journal of Machine Learning Research
Pac-bayesian generalisation error bounds for gaussian process classification
The Journal of Machine Learning Research
Noise in Integrate-and-Fire Neurons: From Stochastic Input to Escape Rates
Neural Computation
The spike response model: a framework to predict neuronal spike trains
ICANN/ICONIP'03 Proceedings of the 2003 joint international conference on Artificial neural networks and neural information processing
How Close Are We to Understanding V1?
Neural Computation
Single neuron computation: From dynamical system to feature detector
Neural Computation
Valuations for spike train prediction
Neural Computation
Feature selection in simple neurons: How coding depends on spiking dynamics
Neural Computation
Journal of Computational Neuroscience
Journal of Computational Neuroscience
Optimization methods for spiking neurons and networks
IEEE Transactions on Neural Networks
Characterizing the fine structure of a neural sensory code through information distortion
Journal of Computational Neuroscience
A systematic method for configuring vlsi networks of spiking neurons
Neural Computation
Motoneuron membrane potentials follow a time inhomogeneous jump diffusion process
Journal of Computational Neuroscience
The neural representation of time: An information-theoretic perspective
Neural Computation
Dynamic state and parameter estimation applied to neuromorphic systems
Neural Computation
Journal of Computational Neuroscience
Learning quadratic receptive fields from neural responses to natural stimuli
Neural Computation
Journal of Computational Neuroscience
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We examine a cascade encoding model for neural response in which a linear filtering stage is followed by a noisy, leaky, integrate-and-fire spike generation mechanism. This model provides a biophysically more realistic alternative to models based on Poisson (memoryless) spike generation, and can effectively reproduce a variety of spiking behaviors seen in vivo. We describe the maximum likelihood estimator for the model parameters, given only extracellular spike train responses (not intracellular voltage data). Specifically, we prove that the log-likelihood function is concave and thus has an essentially unique global maximum that can be found using gradient ascent techniques. We develop an efficient algorithm for computing the maximum likelihood solution, demonstrate the effectiveness of the resulting estimator with numerical simulations, and discuss a method of testing the model's validity using time-rescaling and density evolution techniques.