Wearable wireless sensor network to assess clinical status in patients with neurological disorders
Proceedings of the 6th international conference on Information processing in sensor networks
A sensor-based framework for detecting human gait cycles using acceleration signals
SoftCOM'09 Proceedings of the 17th international conference on Software, Telecommunications and Computer Networks
Monitoring motor fluctuations in patients with Parkinson's disease using wearable sensors
IEEE Transactions on Information Technology in Biomedicine - Special section on body sensor networks
Wearable sensor activity analysis using semi-Markov models with a grammar
Pervasive and Mobile Computing
Energy efficient transmission strategies for body sensor networks with energy harvesting
IEEE Transactions on Communications
Journal of Systems Architecture: the EUROMICRO Journal
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The aim of this study is to identify movement characteristics associated with motor fluctuations in patients with Parkinson's disease by relying on wearable sensors. Improved methods of assessing longitudinal changes in Parkinson's disease would enable optimization of treatment and maximization of patient function. We used eight accelerometers on the upper and lower limbs to monitor patients while they performed a set of standardized motor tasks. A video of the subjects was used by an expert to assign clinical scores. We focused on a motor complication referred to as dyskinesia, which is observed in association with medication intake. The sensor data were processed to extract a feature set responsive to the motor fluctuations. To assess the ability of accelerometers to capture the motor fluctuation patterns, the feature space was visualized using PCA and Sammon's mapping. Clustering analysis revealed the existence of intermediate clusters that were observed when changes occurred in the severity of dyskinesia. We present quantitative evidence that these intermediate clusters are the result of the high sensitivity of the proposed technique to changes in the severity of dyskinesia observed during motor fluctuation cycles.