Computer-Aided Evaluation of Protein Expression in Pathological Tissue Images

  • Authors:
  • Elisa Ficarra;Enrico Macii;Giovanni De Micheli;Luca Benini

  • Affiliations:
  • Politecnico di Torino, Italy;Politecnico di Torino, Italy;Ecole Polythecnique Federale de Lausanne (EPFL), Switzerland;University of Bologna, Spain

  • Venue:
  • CBMS '06 Proceedings of the 19th IEEE Symposium on Computer-Based Medical Systems
  • Year:
  • 2006

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Abstract

This work presents the first fully-automated computeraided analysis approach to the quantification of the expression of receptors for the non-small cell lung carcinoma. This immunohistochemical analysis is usually performed by pathologists via visual inspection of tissue samples images. Our techniques streamlines this error-prone and time-consuming process, thereby facilitating analysis and diagnosis. Experimental results on several real-life datasets demonstrate the high quantitative precision of our approach.