Computational Atlases of Severity of White Matter Lesions in Elderly Subjects with MRI
MICCAI '08 Proceedings of the 11th international conference on Medical Image Computing and Computer-Assisted Intervention - Part I
Multiple sclerosis lesion detection using constrained GMM and curve evolution
Journal of Biomedical Imaging
Detection and segmentation of pathological structures by the extended graph-shifts algorithm
MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention - Volume Part I
Spatial decision forests for MS lesion segmentation in multi-channel MR images
MICCAI'10 Proceedings of the 13th international conference on Medical image computing and computer-assisted intervention: Part I
Atlas guided identification of brain structures by combining 3d segmentation and SVM classification
MICCAI'06 Proceedings of the 9th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
MICCAI'06 Proceedings of the 9th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
GANC: Greedy agglomerative normalized cut for graph clustering
Pattern Recognition
Hi-index | 0.00 |
We present a novel multiscale approach that combines segmentation with classification to detect abnormal brain structures in medical imagery, and demonstrate its utility in detecting multiple sclerosis lesions in 3D MRI data. Our method uses segmentation to obtain a hierarchical decomposition of a multi-channel, anisotropic MRI scan. It then produces a rich set of features describing the segments in terms of intensity, shape, location, and neighborhood relations. These features are then fed into a decision tree-based classifier, trained with data labeled by experts, enabling the detection of lesions in all scales. Unlike common approaches that use voxel-by-voxel analysis, our system can utilize regional properties that are often important for characterizing abnormal brain structures. We provide experiments showing successful detections of lesions in both simulated and real MR images.