Characteristic attributes in cancer microarrays
Journal of Biomedical Informatics
Phylogenetics in the modern era
Journal of Biomedical Informatics - Special issue: Phylogenetic inferencing: Beyond biology
CIBCB'09 Proceedings of the 6th Annual IEEE conference on Computational Intelligence in Bioinformatics and Computational Biology
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Systematic analyses are included as integral parts of bioinformatic analysis. The use of phenetic and phylogenetic trees in many of the newer areas of biology create a need for bioinformaticists to understand more completely the nuances of systematic analysis. Any description in comparative biology, universally begins with what information to use in the comparative endeavor. Phylogenetic approaches are no different. The diversity of approaches and phylogenetic questions in systematics have sometimes hindered a precise understanding of what primary data should be collected to perform such analyses. In addition, one should always keep in mind that the objective of systematic organization of entities in nature not only strives to organize those entities in an objective, repeatable and operational way, but also to organize the attributes of the entities in a similar hierarchical context. This paper attempts to describe characters as the basis of all comparative analysis, to describe the diverse kinds of primary data that exist today in biology, genomics, and bioinformatics, and to place these kinds of primary data in the context of the established approaches to tree building.