AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
Computers and Biomedical Research
Task-Dependent Modulation of Regions in the Left Inferior Frontal Cortex during Semantic Processing
Journal of Cognitive Neuroscience
Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies
Journal of Cognitive Neuroscience
Conceptual Processing during the Conscious Resting State: A Functional MRI Study
Journal of Cognitive Neuroscience
Functional Neuroanatomy of the Semantic System: Divisible by What?
Journal of Cognitive Neuroscience
Segregating semantic from phonological processes during reading
Journal of Cognitive Neuroscience
Common blood flow changes across visual tasks: Ii. decreases in cerebral cortex
Journal of Cognitive Neuroscience
fMRI of Past Tense Processing: The Effects of Phonological Complexity and Task Difficulty
Journal of Cognitive Neuroscience
Age-related Changes in Brain Activity across the Adult Lifespan
Journal of Cognitive Neuroscience
The Perception of Voice Onset Time: An fMRI Investigation of Phonetic Category Structure
Journal of Cognitive Neuroscience
Reading Fluent Speech from Talking Faces: Typical Brain Networks and Individual Differences
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Neural Topography and Content of Movement Representations
Journal of Cognitive Neuroscience
The New Perspectives in fMRI Research Award: Exploring Patterns of Default-Mode Brain Activity
Journal of Cognitive Neuroscience
Deactivations, Global Signal, and the Default Mode of Brain Function
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Multiple Neuronal Networks Mediate Sustained Attention
Journal of Cognitive Neuroscience
Neural Correlates of Lexical Access during Visual Word Recognition
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Functional Interactions during the Retrieval of Conceptual Action Knowledge: An fMRI Study
Journal of Cognitive Neuroscience
Age Differences in Deactivation: A Link to Cognitive Control?
Journal of Cognitive Neuroscience
Cognitive and emotional modulation of brain default operation
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Default-Mode Network Activity Identified by Group Independent Component Analysis
ICIC '07 Proceedings of the 3rd International Conference on Intelligent Computing: Advanced Intelligent Computing Theories and Applications. With Aspects of Artificial Intelligence
Brain activation and deactivation in human inductive reasoning: an fMRI study
BI'10 Proceedings of the 2010 international conference on Brain informatics
Striatal dopamine influences the default mode network to affect shifting between object features
Journal of Cognitive Neuroscience
Retrieval search and strength evoke dissociable brain activity during episodic memory recall
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Negative bold response in the hippocampus during short-term spatial memory retrieval
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
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Task-induced deactivation (TID) refers to a regional decrease in blood flow during an active task relative to a "resting" or "passive" baseline. We tested the hypothesis that TID results from a reallocation of processing resources by parametrically manipulating task difficulty within three factors: target discriminability, stimulus presentation rate, and short-term memory load. Subjects performed an auditory target detection task during functional magnetic resonance imaging (fMRI), responding to a single target tone or, in the short-term memory load conditions, to target sequences. Seven task conditions (a common version and two additional levels for each of the three factors) were each alternated with "rest" in a block design. Analysis of covariance identified brain regions in which TID occurred. Analyses of variance identified seven regions (left anterior cingulate/superior frontal gyrus, left middle frontal gyrus, right anterior cingulate gyrus, left and right posterior cingulate gyrus, left posterior parieto-occipital cortex, and right precuneus) in which TID magnitude varied across task levels within a factor. Follow-up tests indicated that for each of the three factors, TID magnitude increased with task difficulty. These results suggest that TID represents reallocation of processing resources from areas in which TID occurs to areas involved in task performance. Short-term memory load and stimulus rate also predict suppression of spontaneous thought, and many of the brain areas showing TID have been linked with semantic processing, supporting claims that TID may be due in part to suspension of spontaneous semantic processes that occur during "rest" (Binder et al., 1999). The concept that the typical "resting state" is actually a condition characterized by rich cognitive activity has important implications for the design and analysis of neuroimaging studies.